The Sardar Vallabhbhai Patel International Airport serves both domestic and international flights to and from Ahmedabad and the neighboring cities of Surendranagar, Mehsana and Nadiad. The airport connects the city with destinations across India and the world. It is the busiest airport in Gujarat, and one of the busiest in India. In 2008 the airport served 5,372,259 passengers.

Ahmedabad is one of the six operating divisions of the Western Railway. Railway lines connect the city to all towns in Gujarat and other major Indian cities like Delhi, Mumbai, Kolkata, Chennai, Pune, Indore, Bhopal, Lucknow, Jaipur, Jabalpur, Raipur, Hyderabad, Nagpur etc. The Ahmedabad Railway Station, locally known as Kalupur Railway Station is the city's main terminus; Ahmedabad's other stations are Maninagar, Vatva, Gandhigram, Asarva, Chandlodia, Kali gam, Vastrapur, Sabarmati, Sarkhej, Naroda, Aamli.
The state government has registered MetroLink Express Gandhinagar and Ahmedabad Company Ltd as a special purpose vehicle (SPV) for the metro rail project connecting Ahmedabad with Gandhinagar. The state government plans to use this SPV as a nodal agency to implement the metro and regional rail project based on public-private partnership for Ahmedabad Region and Gandhinagar Cosmopolitan Region.